RESEARCH
Expertise
Dr. Parangi is one of a handful of endocrine surgeons with expertise in molecular biology and has over 100 publications, many on thyroid cancer therapeutics as well as management of hyperparathyroidism in peer-reviewed premiere journals. Dr. Parangi has won numerous awards for her research on understanding the role of the BRAF oncoprotein, why some patients with thyroid cancer do worse than others, and how to help them. Her work in thyroid cancer details certain key genetic changes seen more frequently in those who do poorly, to help understand the role of these genetic changes in the aggressive behavior of those cancers. This important research effort focuses on clarifying the molecular mechanism of thyroid cancer invasion and understanding the process of disease progression in patients with thyroid cancer.
Her current projects focus on understanding the role of the immune system in the tumor microenvironment and how immunotherapy can be utilized to treat aggressive thyroid cancers such as anaplastic thyroid cancer. She accepts both graduate students and post-doctoral fellows in her research laboratory. She has worked successfully with industry partners to bring novel drugs for thyroid cancer to clinical trials.
